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"Most women will require 46 months of metformin therapy before they achieve ovulatory menses." Obstetrics & Gynecology If regular ovulation hasn't resumed after six months, healthcare providers may explore additional options, such as combining metformin with other medications or using cyclic progestin therapy to protect endometrial health

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SJ Dixon: conceptualization, formal analysis, supervision, funding acquisition, methodology, project administration, and writingoriginal draft, review, and editing